Buy PT-141 research peptide (10 mg vial or 10-pack) for in-vitro laboratory research. Every lot is tested by HPLC and mass spectrometry and comes with a batch-specific Certificate of Analysis.
About PT-141
PT-141 is a synthetic cyclic heptapeptide (Ac-Nle-cyclo[Asp-His-D-Phe-Arg-Trp-Lys]-OH) studied as an agonist at melanocortin receptor subtypes MC3R and MC4R. Alchemy Gold Research supplies PT-141 as a lyophilized powder for in-vitro laboratory research. Every lot is tested by HPLC and mass spectrometry and ships with a batch-specific Certificate of Analysis (COA).
Research background
In the research literature, PT-141 serves as a tool compound for studying melanocortin receptor pharmacology in transfected cell lines expressing MC3R and MC4R. Cell-based assays examine receptor-binding affinity, G-protein coupled signaling, and cAMP accumulation following receptor engagement. Researchers use these models to characterize receptor selectivity between MC3R and MC4R subtypes. Most published work on PT-141 is preclinical. It has not been approved for human or veterinary use, and it is supplied here for laboratory research only. Researchers typically run it alongside vehicle and reference-agonist controls within a single lot.
Studied research pathways
- MC3R receptor binding. Transfected cell assays examining ligand binding at MC3R.
- MC4R receptor activation. Cell-based assays studying agonist activation of MC4R signaling.
- cAMP signaling. Assays measuring cAMP accumulation downstream of receptor activation.
Quality and documentation
Every lot of PT-141 is tested by HPLC for purity and by mass spectrometry for molecular identity, and it is released with a batch-specific Certificate of Analysis (COA) that lists the lot number, test date, purity and mass result. Testing is carried out by an independent third-party laboratory. The exact values for the lot you receive are printed on its COA.
Storage and handling
Store the lyophilized powder at −20 °C (−4 °F), protected from light. Keep the vial sealed until you are ready to use it, and let it come to room temperature before opening to limit moisture condensation. Solvents, concentrations and handling protocols are set by your research team and your institution's safety procedures.
Frequently asked questions
- Is PT-141 approved for human use?
- No. PT-141 is sold for in-vitro laboratory research only. It is not a drug, food or supplement, and it is not approved by the FDA for human or veterinary use.
- What purity do you test for?
- Every lot is tested by HPLC, and the product specification is ≥98% purity. The measured value for your lot is printed on its batch-specific COA.
- Where do I find the COA?
- A batch-specific COA accompanies each lot. If you have a question about a COA, contact us and include the lot number.
- Who can buy PT-141?
- Qualified researchers and laboratories that accept our Research Use Only (RUO) policy. The policy page lists the conditions of purchase.
- Is PT-141 a linear peptide?
- No. PT-141 is a cyclic heptapeptide, with a ring formed between the Asp and Lys residues in its sequence, rather than a linear chain.
Why order from us
- Flat-rate shipping on every order. Delivery is typically 1 to 5 days, depending on your location.
- Same-day shipping on orders placed by 4 PM PST. For a faster, custom delivery speed, call us.
- Volume pricing on 10-packs, shown with the size options above.
- Support by phone from 8 am to 8 pm Pacific on (725) 222-3886, or by email at info@alchemygoldresearch.com.
Related
Research Library
For laboratory research use only. Not for human consumption. Not approved by the FDA for human or veterinary use.
US-Based Pharma Grade