Semax is a synthetic heptapeptide (Met-Glu-His-Phe-Pro-Gly-Pro) derived from the ACTH(4–10) fragment, with a C-terminal Pro-Gly-Pro tripeptide added to slow enzymatic degradation. In laboratory research it is used to study neurotrophin (BDNF/TrkB) expression, melanocortin-pathway signaling, and peptide stability in controlled in-vitro and cell-model systems. Supplied as a lyophilized powder in a 10 mg research vial; analytical documentation accompanies each lot.
- Sequence: Met-Glu-His-Phe-Pro-Gly-Pro
- Molecular Formula: C₃₇H₅₁N₉O₁₀S
- Molecular Weight: 813.93 g/mol
- Purity: ≥ 98% (HPLC)
- Form: Lyophilized powder
- Testing: HPLC & mass spectrometry (third-party)
- Storage: Store at −20 °C (−4 °F), protect from light
- Intended Use: In-vitro research use only
Studied research pathways: Neurotrophin (BDNF/TrkB) expression, Melanocortin pathway signaling, Enzymatic stability